The vascular disrupting agents market is projected to be worth USD 2 billion by 2030, growing at an annualized rate of over 60%, claims Roots Analysis
Vascular
disrupting agents (VDAs) are the novel oncology drugs being developed to more
specifically combat complex, life threatening cancer indications
London
Roots Analysis has announced the addition of “Vascular Disrupting Agents Market, 2021-2030” report to its list of offerings.
Despite multiple cancer
treatment options, there is an evident unmet need for anti-cancer therapies
with better efficacy and less toxicity. The vascular
disrupting
agents, which target the established tumor
vasculature and disrupt blood flow to cancerous tissue, have garnered
considerable interest as a novel anticancer therapeutic modality.
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order this 290+ page report, which features 110+ figures and 125+ tables,
please visit https://www.rootsanalysis.com/reports/vascular-disrupting-agents-market.html
Key Market Insights
Currently,
more than 120 vascular disrupting agents are in the development pipeline
Around 50% of the vascular disrupting agents are being
evaluated in phase II clinical trials, while more than 5% are either marketed
or in phase III of development. Examples of phase III drugs include Bavituximab
(non-small cell lung cancer), Icaritin (hepatocellular carcinoma), NGR-TNF
(malignant pleural mesothelioma), Padeliporfin (transitional cell cancer of renal
pelvis and ureter), Plinabulin (non-small cell lung cancer,
chemotherapy-induced neutropenia) and VB-111 (glioblastoma, recurrent platinum
resistant ovarian cancer). Further, 35% molecules are in phase I trials.
Around 30
industry and non-industry players are engaged in the development of vascular
disrupting agents
Around 40% of these firms are
start-ups / small players (with less than 50 employees). It is also worth
highlighting that, majority of the firms engaged in this domain (56%) are based
in North America, followed by Asia Pacific (25%) and Europe (19%).
Over
530 clinical trials are currently evaluating the therapeutic effects of
vascular disrupting agents, worldwide
It is
worth mentioning that most of the trials were / are being conducted in North
America (56%), where more than 40% of the total number of patients had been
enrolled. This is followed by clinical research activity in Europe (24%) and
Asia Pacific (20%).
Around
800 articles related to vascular disrupting agents have been published in
reputed scientific journals, since 2016
More than
30% of the publications mentioned in the report, were focused on the assessment
of treatment safety / effectiveness of various vascular disrupting agents.
Popular journals that have published multiple articles related vascular disrupting
agents, include Scientific Reports, Oncotarget, European Journal of
Medicinal Chemistry, and PLoS One.
Close to 220 grants have been awarded to support research on
vascular disrupting agents, since 2016
An
estimated USD 96 million in grants have been awarded to various companies /
organizations working in this domain, during time period between 2016 and January
2021. Almost 20% of the total grant amount was funded by the National Cancer
Institute.
Over 265
eminent scientists (identified as key opinion leaders (KOLs)) are involved in
the clinical trials of vascular disrupting agents
Around
50% of these KOLs are associated with the organizations based in North America,
followed by those in Asia Pacific (38%) and Europe (12%). Majority of these
KOLs are currently affiliated to hospitals and medical centers.
The market is anticipated to grow at a CAGR of over 60%, during
the period 2021-2030
Growth in this domain is
anticipated to be driven by the drugs that are being developed for the
treatment of non-small cell lung cancer. North America (primarily the US) and
Europe are expected to capture around 50% of the market share by 2030, in terms
of the sales-based revenues.
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Key
Questions Answered
§
Who are the leading industry and non-industry players in this
market?
§
Which cancer indications can be treated with vascular disrupting
agents?
§
Which geographies are the most active in conducting clinical
trials on vascular disrupting agents?
§
What is the focus area of the research activities going on in
this domain?
§
Which are the leading administering institute centers supporting
the research related to this domain?
§
Who are the key opinion leaders that can help you drive your
development efforts?
§
How is the current and future market opportunity likely to be
distributed across key market segments?
The USD 2 billion (by 2030) financial opportunity
within the vascular disrupting agents market has been analyzed across the
following segments:
§
Target Indication
§
Chemotherapy-induced
Neutropenia
§
Glioblastoma
§
Hepatocellular
Carcinoma
§
Malignant Pleural
Mesothelioma
§
Non-Small Cell Lung
Cancer
§
Prostate Cancer
§
Recurrent Platinum
Resistant Ovarian Cancer
§
Transitional Cell
Cancer of Renal Pelvis and Ureter
§
Therapeutic Area
§
Solid Tumors
§
Others
§
Type of Molecule
§
Small Molecules
§
Ligand Directed Agents
§
Type of Therapy
§
Monotherapy
§
Combination Therapy
§
Route of Administration
§
Oral
§
Intravenous
§
Key Geographical Regions
§
North America
§
Europe
§
Asia-Pacific and Rest of the World
The research includes
detailed profiles of key players (listed
below), each profile features an overview of the company, its financial
information (if available), drug portfolio, details on recent
developments, as well as an informed future outlook.
§ Avid
Bioservices
§ Bionomics
§ Iceni
Pharmaceuticals
§ Myrexis
§ Oncotelic
Therapeutics
§ VBL
Therapeutics
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please visit
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