NOVEL DRUG RECONSTITUTION SYSTEMS - CURRENT MARKET LANDSCAPE
Over the years, novel drug reconstitution systems have been
widely adopted in the healthcare sector, owing to the numerous benefits offered
by these products. During our research, we identified over 55 novel
drug reconstitution systems, including prefilled syringes, cartridges and
infusion bags being manufactured to ease the reconstitution of drugs packaged
in containers.
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Majority of the companies (32%) engaged in this domain are very large players. Examples
of such companies include (in
alphabetical order, established after 1900) Baxter, Fresenius Kabi,
ICU Medical, Shandong Pharmaceutical Glass, Terumo, Vetter Pharma and West
Pharmaceutical Services. This is followed by the share of mid-sized players
(29%) in this domain. Prominent
examples of mid-sized players include (in alphabetical order, established after 2000)
ADIENNE, Kapsam, and Taian Youlyy Industrial. Further, majority of the
companies (47%) engaged in this domain are located in Europe, particularly in
Germany. This is followed by the players based in Asia-Pacific region with Japan and South Korea being the most prominent countries. Within
North America, US emerged as the leading region, with the presence of seven
companies.
As can be observed in the figure, majority of the prefilled
syringes (37.5%) and infusion bags (28.6%) are dual chamber systems. On the
other hand, around 18% of the infusion bags are multi chambered. Further, the
cartridges are available with single and dual chambers, which make the
administration of lyophilized drugs possible in an efficient and convenient
manner. Further, most of the prefilled syringes have capacity of 1-2.5 mL.
As can be observed in the figure, plastic (57%) emerged as
the most popular type of container fabrication material used in novel drug
reconstitution systems. Ethylene vinyl acetate (EVA) emerged as the preferred
plastic type used for the fabrication of majority (41%) of novel drug
reconstitution system containers. EVA is a hydrophobic polymer that offers
great flexibility and does not require solvents for drug delivery. Polypropylene, having
demonstrated good impact strength and improved resistance to moisture, is the
next popular material used in the manufacturing of novel drug reconstitution
systems.
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As can be seen in the figure, Nipro and SCHOTT-KAISHA emerged
as the most prominent players in this domain, developing four novel drug
reconstitution systems each. It is worth mentioning that Nipro offers all the
three types of novel drug reconstitution systems, namely- dual chamber
prefilled syringe (2), dual chamber cartridge (1), and dual chamber infusion
bag.
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